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case western reserve university

DEPT OF STATISTICS

 

SEMINARS

 

 
Fall 2007
STATISTICS COLLOQUIUM

 

Wednesday, October 1, 2008
3:30-4:00—Refreshments
4:00-5:00—Talk
Yost Hall, Room 101

Curtis Tatsuoka, Ph.D.

Department of Quantitative Health Sciences, Cleveland Clinic

Sequential testing in classification on partially ordered models

Partially ordered sets are natural models for many statistical applications. For instance, in modeling cognitive functioning, it may be natural to assume that certain states have higher levels of functionality than others, and hence to assume that the respective states follow a partial ordering. Another important application involves group testing, where it is of interest to classify objects as defective or non-defective through the sequential testing of pooled objects.
A statistical framework will be described for the problem when there exists a “true” state among a collection of states, and observations from sequentially selected experiments are used to identify it. An advantage to sequentially selecting experiments is that testing burdens can be greatly reduced. Results on asymptotically optimal sequential selection of experiments will be described in the context of Bayesian classification problems when the parameter space is a finite lattice. Experiment selection rules and the attainment of optimal rates of convergence will be discussed.
Finally, an analysis of neuropsychological testing data will be presented. Neuropsychological testing is used to detect changes in cognition in clinical settings.