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case western reserve university

DEPT OF STATISTICS

 

SEMINARS

 

Spring 2005
STATISTICS COLLOQUIUM

 

Friday, March 25, 2005
2:30-3:00—Refreshments
3:00-4:00—Talk
Yost Hall, Room 300

Vanja Dukic

University of Chicago, Department of Health Studies

Optimal Survival Curve Ranking (OSCR): Application to AIDS Reporting Delay

Time delay between a new AIDS diagnosis and its report to the CDC, historically ranging between couple of weeks and couple of years, presents a significant problem when trying to predict future AIDS incidence and health care burden. The reporting delay needs to be correctly estimated and adjusted for in order to avoid potentially serious downward bias. We examine case reports from 39 large US cities, received by the CDC as of the end of December 2001 and published in the APIDS database. We employ Bayesian multi-resolution methodology to estimate city-specific hazards of reporting delay, adjusting for patient covariates and within-city correlation. We describe the ranking of the 39 US cities according to their reporting delay distributions based on the optimal survival curve ranking (OSCR) procedure. We discuss uncertainty in the reported delay estimates and in the resulting ranking, and a way to visualize this uncertainty.